DS-8587
Product Specifications
CAS Number
1356918-39-2
Target
Others, Antibacterial
Related Pathways
Microbiology/Virology, Others
Bioactivity
DS-8587 is a DNA topoisomerase inhibitor. DS-8587 exhibits potent antibacterial activity against quinolone-resistant A. baumannii isolates that harbor mutations in quinolone resistance-determining regions. DS-8587 significantly reduces the number of viable bacteria in a murine model of F. necrophorum-induced liver abscess. In the presence of the efflux pump inhibitor 1- (1-napthylmethyl) -piperazine, no significant changes were observed in the MIC for DS-8587.
Smiles
CC1=C2N([C@H]3[C@H](C3)F)C=C(C(C2=CC(F)=C1N4C[C@@]5([C@](C4)(CCC5)N)F)=O)C(O)=O.Cl.O.O
Molecular Formula
C21H27ClF3N3O5
Molecular Weight
493.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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