DNS-8254
Product Specifications
CAS Number
1821107-98-5
Target
Others, PDE
Related Pathways
Others, Metabolism
Bioactivity
DNS-8254 is a potent and selective Phosphodiesterase 2 (PDE2) inhibitor for the treatment of Memory Disorders (hPDE2a IC50 = 8 nM, Rat Cl-int = 25.6 uL/min/mg) . DNS-8254 demonstrated significant memory enhancing effects in a rat model of novel object recognition.
Smiles
CC=1C=C(N2C(N1)=NC=N2)[C@@H]3CN(C(=O)C4=CC(Br)=C(F)C=C4)CC(F)(F)C3
Molecular Formula
C18H15BrF3N5O
Molecular Weight
454.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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