Salidroside
Product Specifications
CAS Number
10338-51-9
Target
Apoptosis, mTOR, PTEN, Prolyl Endopeptidase (PREP)
Related Pathways
Metabolism, PI3K/Akt/mTOR signaling, Apoptosis, Proteases/Proteasome
Purity
0.9925
Bioactivity
Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor. Salidroside can alleviate cachexia symptoms in a tumor cachexia mouse model by activating mTOR signaling and protect dopaminergic neurons by enhancing PINK1/Parkin-mediated mitochondrial autophagy. Salidroside can also inhibit the growth of cancer cells by regulating the CDK4-cyclin D1 pathway to block the G1 phase and/or regulating the Cdc2-cyclin B1 pathway to block the G2 phase.
Smiles
OCC1OC(OCCc2ccc(O)cc2)C(O)C(O)C1O
Molecular Formula
C14H20O7
Molecular Weight
300.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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