Diazaborine
Product Specifications
CAS Number
22959-81-5
Target
Others, Antibacterial
Related Pathways
Microbiology/Virology, Others
Bioactivity
Diazaborine inhibits maturation of rRNAs for the large ribosomal subunit. Diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1. Diazaborine treatment causes, within minutes, a rapid redistribution of the protein from the nucleolus to the periphery of the nucleus, which provides a possible explanation for the effect of diazaborine on rRNA processing.
Smiles
S(=O)(=O)(N1B(O)C=2C(C=N1)=CC=CC2)C3=CC=C(C)C=C3
Molecular Formula
C14H13BN2O3S
Molecular Weight
300.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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