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DCB-3503

Product Specifications

CAS Number

87302-58-7

Target

Others|||HSP|||CDK

Related Pathways

Metabolism|||Cytoskeletal Signaling|||Cell Cycle/Checkpoint|||Others

Bioactivity

Tylophorine analog DCB-3503 is a potential anticancer and immunosuppressive agent. DCB-3503 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. DCB-3503 allosterically regulates the ATPase and chaperone activities of HSC70 by promoting ATP hydrolysis in the presence of specific RNA binding motifs (AUUUA) of cyclin D1 mRNA.

Smiles

O[C@H]1C=2C(=C3C(=C4C2C=C(OC)C(OC)=C4)C=C(OC)C(OC)=C3)CN5[C@]1(CCC5)[H]

Molecular Formula

C24H27NO5

Molecular Weight

409.47

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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