DA-6886
Product Specifications
CAS Number
1645260-76-9
Target
5-HT Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Purity
0.9999
Bioactivity
DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4) . DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels revealed that it inhibited hERG channel current with an pIC50 value of 4.3, indicating that the compound was 1000-fold more selective for the 5-HT4 receptor over hERG channels.
Smiles
Cl.O=C(NCC1CCN(CCCN2N=NC=C2)CC1)C3=CC(Cl)=C(N)C=C3OC
Molecular Formula
C19H28Cl2N6O2
Molecular Weight
443.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
ELI-41110b 96 Tests
Bovine RPE-retinal G protein-coupled receptor, RGR ELISA KIT
Sign In for Pricing
View Details 
ARP51714_P050-HRP 100 µL
ZNF664 Antibody - N-terminal region : HRP (ARP51714_P050-HRP)
Sign In for Pricing
View Details orb2921264-01 20 µg
Recombinant Anabaena variabilis Protein CrcB homolog (crcB)
Sign In for Pricing
View Details