CMP3a
Product Specifications
CAS Number
2225902-88-3
Target
MAPK|||Others
Related Pathways
MAPK|||Others
Bioactivity
CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.
Smiles
O([C@@H](C)C1=C(C(F)(F)F)C=CC=C1)C=2C=C(C=3N4C(=NC3)C=C(C=C4)C5=CN(CCN(C)C)N=C5)SC2C(N)=O
Molecular Formula
C28H27F3N6O2S
Molecular Weight
568.61
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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