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CMP3a

Product Specifications

CAS Number

2225902-88-3

Target

MAPK|||Others

Related Pathways

MAPK|||Others

Bioactivity

CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.

Smiles

O([C@@H](C)C1=C(C(F)(F)F)C=CC=C1)C=2C=C(C=3N4C(=NC3)C=C(C=C4)C5=CN(CCN(C)C)N=C5)SC2C(N)=O

Molecular Formula

C28H27F3N6O2S

Molecular Weight

568.61

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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