CL385319 HCl
Product Specifications
CAS Number
1210501-46-4
Target
Endogenous Metabolite, Others
Related Pathways
Metabolism, Others
Bioactivity
CL385319 is a potent inhibitor of H5N1 avian influenza A virus infection by blocking viral entry. CL-385319 is effective in inhibiting infection of highly pathogenic H5N1 influenza A virus in Madin-Darby Canine Kidney (MDCK) cells with an IC50 of 27.03±2.54 μM. CL385319 with low cytotoxicity (CC50=1.48±0.01 mM) could also inhibit entry of pseudoviruses carrying hemagglutinins from H5N1 strains that were isolated from different places at different times, while it had no inhibitory activity on the entry of VSV-G pseudotyped particles.
Smiles
Cl.O=C(NCCN1CCCCC1)C2=CC(F)=CC(=C2)C(F)(F)F
Molecular Formula
C15H19ClF4N2O
Molecular Weight
354.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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