CK59
Product Specifications
CAS Number
926319-75-7
Target
CaMK, Others
Related Pathways
Others, Neuroscience
Bioactivity
CK59 is a reversible inhibitor of calcium-calmodulin-dependent kinase II (CaMKII) . CK59 inhibits multiple voltage-gated calcium channels, including the L-type channel during depolarization in a dose-dependent manner. The IC50 for CK59 was approximately 50 μM, which is only five fold larger than the reported IC50 values for CaMKII inhibition.
Smiles
C(C)(C)N1C=2C(=C(NCCCCCCNC(OC(C)(C)C)=O)N=C(NCCO)N2)N=C1
Molecular Formula
C21H37N7O3
Molecular Weight
435.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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