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CK59

Product Specifications

CAS Number

926319-75-7

Target

CaMK|||Others

Related Pathways

Others|||Neuroscience

Bioactivity

CK59 is a reversible inhibitor of calcium-calmodulin-dependent kinase II (CaMKII) . CK59 inhibits multiple voltage-gated calcium channels, including the L-type channel during depolarization in a dose-dependent manner. The IC50 for CK59 was approximately 50 ?M, which is only five fold larger than the reported IC50 values for CaMKII inhibition.

Smiles

C(C)(C)N1C=2C(=C(NCCCCCCNC(OC(C)(C)C)=O)N=C(NCCO)N2)N=C1

Molecular Formula

C21H37N7O3

Molecular Weight

435.56

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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