IWP-2
Product Specifications
CAS Number
686770-61-6
Target
Porcupine, Casein Kinase, Wnt/beta-catenin
Related Pathways
Stem Cells, Cytoskeletal Signaling, Metabolism
Purity
0.9976
Bioactivity
IWP-2 is a Wnt pathway inhibitor (IC50=27 nM) and an ATP-competitive CK1δ inhibitor (IC50=40 nM for M82FCK1δ) . IWP-2 inhibits self-renewal of embryonic stem cells and has been used in stem cell and organoid research.
Smiles
Cc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccccc3)sc2c1
Molecular Formula
C22H18N4O2S3
Molecular Weight
466.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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