IWP-2

Product Specifications

CAS Number

686770-61-6

Target

Porcupine|||Casein Kinase|||Wnt/beta-catenin

Related Pathways

Stem Cells|||Cytoskeletal Signaling|||Metabolism

Purity

0.9976

Bioactivity

IWP-2 is a Wnt pathway inhibitor (IC50=27 nM) and an ATP-competitive CK1? inhibitor (IC50=40 nM for M82FCK1?) . IWP-2 inhibits self-renewal of embryonic stem cells and has been used in stem cell and organoid research.

Smiles

Cc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccccc3)sc2c1

Molecular Formula

C22H18N4O2S3

Molecular Weight

466.6

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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