Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Ceralasertib formate

Product Specifications

CAS Number

1352280-98-8

Target

Others, ATM/ATR

Related Pathways

Others, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair

Bioactivity

Ceralasertib is an orally available inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase. Ceralasertib selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR-mediated signaling, and results in the inhibition of DNA damage checkpoint activation, disruption of DNA damage repair, and the induction of tumor cell apoptosis.

Smiles

OC=O.C[C@@H]1COCCN1c1cc(nc(n1)-c1ccnc2[nH]ccc12)C1(CC1)[S@](C)(=N)=O

Molecular Formula

C21H26N6O4S

Molecular Weight

458.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Dystrophin (3B7) : m-IgGκ BP-HRP Bundle
sc-533944 1 Kit

Dystrophin (3B7) : m-IgGκ BP-HRP Bundle

Sign In for Pricing
View Details
Human UFM1 Affinity Purified Polyclonal Ab
AF8237 100 µg

Human UFM1 Affinity Purified Polyclonal Ab

Sign In for Pricing
View Details
ABHD7 antibody
70R-7489 50 ug

ABHD7 antibody

Sign In for Pricing
View Details
FAM8A1 (NM_016255) Human Tagged ORF Clone Lentiviral Particle
RC208511L1V 200 µL

FAM8A1 (NM_016255) Human Tagged ORF Clone Lentiviral Particle

Sign In for Pricing
View Details
Porcine salivary amylaseα1 (AMYα1) ELISA Kit
YP-W80687-01 48 Tests

Porcine salivary amylaseα1 (AMYα1) ELISA Kit

Sign In for Pricing
View Details
Porcine salivary amylaseα1 (AMYα1) ELISA Kit
YP-W80687-02 96 Tests

Porcine salivary amylaseα1 (AMYα1) ELISA Kit

Sign In for Pricing
View Details