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Butaprost

Product Specifications

CAS Number

69685-22-9

Target

TGF-beta/Smad|||Others|||Prostaglandin Receptor

Related Pathways

Immunology/Inflammation|||Others|||Stem Cells|||GPCR/G Protein

Bioactivity

Butaprost is a chemical compound that functions as a selective agonist for the prostaglandin E receptor (EP2) . It exhibits an EC50 of 33 nM and a Ki of 2.4 ?M when interacting with the murine EP2 receptor. However, Butaprost demonstrates lower activity against murine EP1, EP3, and EP4 receptors. Furthermore, it effectively attenuates fibrosis by inhibiting the TGF-?/Smad2 signaling pathway [1] [2] [3].

Smiles

[C@@H](C/C=C/[C@@H]1[C@@H](CCCCCCC(OC)=O)C(=O)C[C@H]1O)(O)C2(CCC)CCC2

Molecular Formula

C24H40O5

Molecular Weight

408.57

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/64404B5D-0360-40AA-AD38-60586E302ACC/T26925

Available Sizes

Curated Selection

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