Butaprost
Product Specifications
CAS Number
69685-22-9
Target
TGF-beta/Smad|||Others|||Prostaglandin Receptor
Related Pathways
Immunology/Inflammation|||Others|||Stem Cells|||GPCR/G Protein
Bioactivity
Butaprost is a chemical compound that functions as a selective agonist for the prostaglandin E receptor (EP2) . It exhibits an EC50 of 33 nM and a Ki of 2.4 ?M when interacting with the murine EP2 receptor. However, Butaprost demonstrates lower activity against murine EP1, EP3, and EP4 receptors. Furthermore, it effectively attenuates fibrosis by inhibiting the TGF-?/Smad2 signaling pathway [1] [2] [3].
Smiles
[C@@H](C/C=C/[C@@H]1[C@@H](CCCCCCC(OC)=O)C(=O)C[C@H]1O)(O)C2(CCC)CCC2
Molecular Formula
C24H40O5
Molecular Weight
408.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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