BRD0476
Product Specifications
CAS Number
1314958-91-2
Target
Apoptosis, Others
Related Pathways
Others, Apoptosis
Bioactivity
BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ) -induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote β-cell survival. BRD0476 inhibits JAK-STAT signaling without suppressing the kinase activity of any JAK.
Smiles
N(C(NC=1C2=C(C=CC1)C=CC=C2)=O)C3=C4C(C(=O)N([C@H](CO)C)C[C@@H](C)[C@H](CN(S(=O)(=O)C=5C=C6C(=CC5)OCCO6)C)O4)=CC=C3
Molecular Formula
C35H38N4O8S
Molecular Weight
674.76
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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