BMS-933043
Product Specifications
CAS Number
1221973-93-8
Target
AChR, Others
Related Pathways
Neuroscience, Others
Bioactivity
BMS-933043 is a Selective α7 nAChR partial agonist. BMS-933043 showed potent binding affinity to native rat (Ki = 3.3 nM) and recombinant human alpha7 nicotinic acetylcholine receptors (Ki = 8.1 nM) . BMS-933043 shows agonist activity in a calcium fluorescence assay (EC50 = 23.4 nM) and whole cell voltage clamp electrophysiology (EC50 = 0.14 μM (rat) and 0.29 μM (human) ) .
Smiles
N(C=1O[C@@]2(C3CCN(C2)CC3)CN1)C=4C=C(N=CN4)N5C=CN=C5
Molecular Formula
C16H19N7O
Molecular Weight
325.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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