BMS 182874
Product Specifications
CAS Number
153042-42-3
Target
Endothelin Receptor
Related Pathways
GPCR/G Protein
Purity
0.9973
Bioactivity
BMS 182874 is an orally effective and highly selective endothelin receptor ETA antagonist with an IC50 value of 0.150 μM for ETA and a Ki value of 0.055 μM for ETA.BMS 182874 is able to reduce arterial pressure in a rat hypertension model induced by Deoxycorticosterone acetate. BMS 182874 was able to reduce Deoxycorticosterone-induced arterial pressure in a rat model of hypertension and can be used to study cardiovascular disease.
Smiles
S(NC1=C(C)C(C)=NO1)(=O)(=O)C=2C3=C(C(N(C)C)=CC=C3)C=CC2
Molecular Formula
C17H19N3O3S
Molecular Weight
345.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rabbit Polyclonal PKR [p Thr446] Antibody](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NB100-82156-0.025mL 0.025 mL
Rabbit Polyclonal PKR [p Thr446] Antibody
Sign In for Pricing
View Details ![Rabbit Polyclonal UROS Antibody [Alexa Fluor 700]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NBP2-97299AF700 0.1 mL
Rabbit Polyclonal UROS Antibody [Alexa Fluor 700]
Sign In for Pricing
View Details 