Bisnorcymserine
Product Specifications
CAS Number
219920-81-7
Target
Others, Cholinesterase (ChE)
Related Pathways
Others, Neuroscience
Bioactivity
Bisnorcymserine is a reversible inhibitor of butyrylcholinesterase. The leaving group, bisnoreseroline, interacts in a non-covalent way with Ser (200) and His (440), disrupting the existing interactions within the catalytic triad, and it stacks with Trp (84) at the bottom of the gorge, giving rise to an unprecedented hydrogen-bonding contact.
Smiles
C[C@]12C=3C(N[C@]1(NCC2)[H])=CC=C(OC(NC4=CC=C(C(C)C)C=C4)=O)C3
Molecular Formula
C21H25N3O2
Molecular Weight
351.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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