BIPM
Product Specifications
CAS Number
1070424-33-7
Target
Others, ROCK
Related Pathways
Others, Cytoskeletal Signaling, Cell Cycle/Checkpoint, Stem Cells
Bioactivity
BIPM is a potent inhibitor of Rho-associated protein kinase 2 (ROCK2) . Exposure of SH-SY5Y cells to BIPM led to significant changes in cell migration, actin stress fibers and neurite length. BIPM significantly inhibits phosphorylation of cofilin, a regulatory protein of actin cytoskeleton.
Smiles
C(C=1C2=C(C=CC1)C=NC=C2)N3CC(C(=O)C=4C=C5C(=CC4)OCO5)CCC3
Molecular Formula
C23H22N2O3
Molecular Weight
374.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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