Bim-BLK-A
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
Bim-BLK-A efficiently blocks Bim-induced apoptosis after Bax is activated on the mitochondria. The cellular target of Bim-BLK-A was identified to be the succinate dehydrogenase subunit B (SDHB) protein of complex II of the mitochondrial electron transfer chain (ETC) . Bim-BLK-A protects the integrity of the ETC and allows treated cells to continue to proliferate after apoptosis induction.
Smiles
O=C1C=CC(C2=NC(S(=O)(C)=O)=NC(C(F)(F)F)=C2)=CN1CC3=CC=C(OC)C(OC)=C3
Molecular Formula
C20H18F3N3O5S
Molecular Weight
469.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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