BH3I-2'
Product Specifications
CAS Number
315195-18-7
Target
Others
Related Pathways
Others
Bioactivity
BH3I-2' is a cell-permeable BH3 mimetic. BH3I-2' induces apoptosis by specifically preventing BH3 domain-mediated interactions between pro-apoptotic and anti-apoptotic members of the Bcl-2 family, thereby blocking the interaction between Bcl-x and Bak BH3 by targeting the Bcl-x binding pocket.
Smiles
S(=O)(=O)(C1=CC(NC(=O)C2=C(O)C(I)=CC(Cl)=C2)=C(Cl)C=C1)C3=CC=C(Cl)C=C3
Molecular Formula
C19H11Cl3INO4S
Molecular Weight
582.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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