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Bencycloquidium Bromide

Product Specifications

CAS Number

860804-18-8

Target

Others, AChR

Related Pathways

Neuroscience, Others

Bioactivity

Bencycloquidium Bromide is a muscarinic M3 antagonist. Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis. Bencycloquidium Bromide showed high affinity toward the M (3) receptor in Chinese hamster ovary (CHO) cells (M (1) pKi=7.86, M (2) pKi=7.21, M (3) pKi=8.21) ; pA (2) =8.85, 8.71 and 8.57 in methacholine-induced contraction of trachea, ileum and urinary bladder, 8.19 in methacholine-induced bradycardia of right atrium in vitro, respectively.This compound is unstable in powder form and other related salt forms are recommended.

Smiles

[Br-].OC(C=1C=CC=CC1)(COC2C[N+]3(C)CCC2CC3)C4CCCC4

Molecular Formula

C21H32BrNO2

Molecular Weight

410.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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