BBR 2160
Product Specifications
CAS Number
118587-22-7
Target
Calcium Channel|||Others
Related Pathways
Metabolism|||Membrane transporter/Ion channel|||Others
Bioactivity
BBR 2160 is a dihydropyridine derivative belonging to the group of the so-called tiampidine. BBR 2160 has calcium-antagonistic properties in cardiac tissue. Intracellular microelectrodes have been used to characterize the electrophysiological properties of BBR 2160 on guinea-pig papillary muscle and sheep Purkinje fibres. BBR 2160 (10 (-7) and 10 (-6) M) dose dependently decreased the contractility of driven papillary muscle and Purkinje fibre. This effect was associated with a lowering of the plateau phase and a shortening of action potential duration in papillary muscle.
Smiles
C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1CSCCNC=O)C2=CC(N(=O)=O)=CC=C2
Molecular Formula
C21H25N3O7S
Molecular Weight
463.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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