AZD-9164 bromide
Product Specifications
CAS Number
1034916-72-7
Target
AChR, Others
Related Pathways
Neuroscience, Others
Bioactivity
AMG-221 is a potent and selective 11β-HSD1 inhibitor. AMG 221 potently blocked 11β-HSD1 activity, producing sustained inhibition for the 24-hour study duration as measured in ex vivo adipose samples. AMG-221 decreased fed blood glucose and insulin levels and reduced body weight in diet-induced obesity mice.
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C(CC1=CC=C(F)C=C1)[N+]23C[C@H](OC([C@](C)(C4=CC=CC=C4)N5CCCCC5)=O)C(CC2)CC3.[Br-]
Molecular Formula
C29H38BrFN2O2
Molecular Weight
545.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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