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Azadirone

Product Specifications

CAS Number

30002-86-9

Target

TNF, Bcl-2 Family, Parasite, Others

Related Pathways

Apoptosis, Microbiology/Virology, Others

Bioactivity

Azadirone is a limonoid tetranortriterpene. Azadirone can sensitize cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through ROS-ERK-CHOP-mediated up-regulation of DR4 and DR5 signaling, down-regulation of cell survival proteins, and up-regulation of proapoptotic proteins.

Smiles

[H][C@@]12CO[C@@H](CN(N=O)C(N)=O)[C@]1([H])OC(C)(C)O2

Molecular Formula

C9H15N3O5

Molecular Weight

245.23

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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