AZ-4217

Product Specifications

CAS Number

1383846-83-0

Target

Beta-Secretase, Others

Related Pathways

Neuroscience, Others

Bioactivity

AZ-4217 is a high potency BACE inhibitor. It displays acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice. AZ-4217 has IC50 160 pM in human SH-SY5Y cells with an excellent in vivo efficacy.

Smiles

NC1=N[C@](C=2C1=C(F)C=CC2)(C3=CN(CC)C(=O)C(C)=C3)C4=CC(=CC=C4)C=5C=C(C#CC)C=NC5

Molecular Formula

C30H25FN4O

Molecular Weight

476.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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