AZ-4217
Product Specifications
CAS Number
1383846-83-0
Target
Beta-Secretase, Others
Related Pathways
Neuroscience, Others
Bioactivity
AZ-4217 is a high potency BACE inhibitor. It displays acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice. AZ-4217 has IC50 160 pM in human SH-SY5Y cells with an excellent in vivo efficacy.
Smiles
NC1=N[C@](C=2C1=C(F)C=CC2)(C3=CN(CC)C(=O)C(C)=C3)C4=CC(=CC=C4)C=5C=C(C#CC)C=NC5
Molecular Formula
C30H25FN4O
Molecular Weight
476.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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