AZ10397767

Product Specifications

CAS Number

333742-63-5

Target

Others|||CXCR

Related Pathways

Others|||GPCR/G Protein|||Autophagy|||Immunology/Inflammation

Bioactivity

AZ10397767 is a potent CXCR2 antagonist (IC50 = 1 nM) . AZ10397767 significantly reduced the numbers of infiltrating neutrophils into both in vitro and in vivo tumor models.

Smiles

N([C@@H](CO)C)C1=C2C(=NC(SCC3=C(F)C(Cl)=CC=C3)=N1)NC(=O)S2

Molecular Formula

C15H14ClFN4O2S2

Molecular Weight

400.88

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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