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Berzosertib

Product Specifications

CAS Number

1232416-25-9

Target

ATM/ATR

Related Pathways

DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling

Purity

>99.99%

Bioactivity

Berzosertib (VE-822) is an ATR inhibitor (Ki<0.2 nM) that also inhibits ATM (Ki=34 nM) . Berzosertib has antitumor activity and has been used in trials investigating the treatment of ovarian tumors, plasmacytoid tumors of the ovary, solid tumors in adults, advanced solid tumors, and advanced solid tumors.

Smiles

CNCc1ccc(cc1)-c1cc(on1)-c1nc(cnc1N)-c1ccc(cc1)S(=O)(=O)C(C)C

Molecular Formula

C24H25N5O3S

Molecular Weight

463.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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