Berzosertib
Product Specifications
CAS Number
1232416-25-9
Target
ATM/ATR
Related Pathways
DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling
Purity
>99.99%
Bioactivity
Berzosertib (VE-822) is an ATR inhibitor (Ki<0.2 nM) that also inhibits ATM (Ki=34 nM) . Berzosertib has antitumor activity and has been used in trials investigating the treatment of ovarian tumors, plasmacytoid tumors of the ovary, solid tumors in adults, advanced solid tumors, and advanced solid tumors.
Smiles
CNCc1ccc(cc1)-c1cc(on1)-c1nc(cnc1N)-c1ccc(cc1)S(=O)(=O)C(C)C
Molecular Formula
C24H25N5O3S
Molecular Weight
463.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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