JNK-IN-8
Product Specifications
CAS Number
1410880-22-6
Target
JNK, c-Kit
Related Pathways
Tyrosine Kinase/Adaptors, MAPK
Purity
>99.99%
Bioactivity
JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM) with over 10-fold selectivity compared to MNK2 and Fms, and no inhibition of Met, c-Kit, or PDGFRβ in the A375 cell line.
Smiles
CN(C)CC=CC(=O)Nc1cccc(c1)C(=O)Nc1ccc(Nc2nccc(n2)-c2cccnc2)c(C)c1
Molecular Formula
C29H29N7O2
Molecular Weight
507.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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