AM-1430
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
AM-1430 is a potent and selective PI3Kδ inhibitor. AM-1430 has cellular potency: pAKT IC50 = 0.8 nM; HWB, u (pAKT) IC 50 = 7.7 nM. Rat KLH: IgG ED50 -= 0.016 mg/kg; IhM ED50 = 0.015 mg/kg. Rat PK Clu = 1.7 L/hr/kg.
Smiles
CNC(C1=C(C2=NC=CC=C2)C([C@H](C)NC3=NC=NC(N)=C3C#N)=NC4=CC=CC(F)=C14)=O
Molecular Formula
C23H19FN8O
Molecular Weight
442.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
M06609-carrier-free 100 µL
Anti-Calmodulin Rabbit Monoclonal Antibody, Carrier-free
Sign In for Pricing
View Details 
MBS6470501-01 0.2 mL
CKMT1A, NT (Creatine Kinase U-type, Mitochondrial, Ubiquitous Mitochondrial Creatine Kinase, U-MtCK, Acidic-type Mitochondrial Creatine Kinase, Mia-CK, CKMT1A, CKMT, CKMT1B, CKMT) (AP)
Sign In for Pricing
View Details MBS6470501-02 5x 0.2 mL
CKMT1A, NT (Creatine Kinase U-type, Mitochondrial, Ubiquitous Mitochondrial Creatine Kinase, U-MtCK, Acidic-type Mitochondrial Creatine Kinase, Mia-CK, CKMT1A, CKMT, CKMT1B, CKMT) (AP)
Sign In for Pricing
View Details 214661-ML750 100 µL
CD305 (LAIR-1, Leukocyte-Associated Ig-like Receptor-1) (MaxLight 750) discontinued
Sign In for Pricing
View Details