AK301
Product Specifications
CAS Number
314022-97-4
Target
Apoptosis, Microtubule Associated
Related Pathways
Apoptosis, Cytoskeletal Signaling
Purity
0.9975
Bioactivity
AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM) . Colon cancer cells arrested in mitosis with AK301 readily underwent a p53-dependent apoptosis following compound withdrawal and arrest release.
Smiles
C(=O)(C1=C(OCC)C=CC=C1)N2CCN(CC2)C3=CC(Cl)=CC=C3
Molecular Formula
C19H21ClN2O2
Molecular Weight
344.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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