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AG-7404

Product Specifications

CAS Number

343565-99-1

Target

Virus Protease|||Others

Related Pathways

Others|||Microbiology/Virology

Bioactivity

AG-7404 is a potent protease inhibitor with anti-poliovirus activity. AG-7404 was active against all virus with EC50 values ranging from 0.080 to 0.674 ?M. AG-7404 was fully active against V-073-resistant variants with EC50 values ranging from 0.218 to 0.819 ?M, compared to values ranging from 0.202 to 0.407 ?M for the V-073-susceptible parental strains.

Smiles

[C@@H](C(N[C@@H](C[C@H]1C(=O)NCC1)/C=C/C(OCC)=O)=O)(CC#C)N2C(=O)C(NC(=O)C3=NOC(C)=C3)=CC=C2

Molecular Formula

C26H29N5O7

Molecular Weight

523.54

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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