AG-7404
Product Specifications
CAS Number
343565-99-1
Target
Virus Protease, Others
Related Pathways
Others, Microbiology/Virology
Bioactivity
AG-7404 is a potent protease inhibitor with anti-poliovirus activity. AG-7404 was active against all virus with EC50 values ranging from 0.080 to 0.674 μM. AG-7404 was fully active against V-073-resistant variants with EC50 values ranging from 0.218 to 0.819 μM, compared to values ranging from 0.202 to 0.407 μM for the V-073-susceptible parental strains.
Smiles
[C@@H](C(N[C@@H](C[C@H]1C(=O)NCC1)/C=C/C(OCC)=O)=O)(CC#C)N2C(=O)C(NC(=O)C3=NOC(C)=C3)=CC=C2
Molecular Formula
C26H29N5O7
Molecular Weight
523.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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