A 65281
Product Specifications
CAS Number
111279-49-3
Target
Others, DNA/RNA Synthesis, Antibacterial
Related Pathways
Others, Microbiology/Virology, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
A 65281 is an antibacterial isothiazoloquinolone and a potent inhibitor of the P4-unknotting reaction. It induces considerable DNA breakage mediated by calf thymus topoisomerase II.
Smiles
FC1=C2N(C3=C(C(=O)C2=CC(F)=C1N4CCNCC4)C(=O)NS3)C5CC5
Molecular Formula
C17H16F2N4O2S
Molecular Weight
378.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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