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A 65281

Product Specifications

CAS Number

111279-49-3

Target

Others, DNA/RNA Synthesis, Antibacterial

Related Pathways

Others, Microbiology/Virology, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

Bioactivity

A 65281 is an antibacterial isothiazoloquinolone and a potent inhibitor of the P4-unknotting reaction. It induces considerable DNA breakage mediated by calf thymus topoisomerase II.

Smiles

FC1=C2N(C3=C(C(=O)C2=CC(F)=C1N4CCNCC4)C(=O)NS3)C5CC5

Molecular Formula

C17H16F2N4O2S

Molecular Weight

378.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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