PD173074

Product Specifications

CAS Number

219580-11-7

Target

FGFR|||EGFR|||Apoptosis|||VEGFR|||IGF-1R|||Src

Related Pathways

Angiogenesis|||Apoptosis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

Purity

0.9821

Bioactivity

PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.

Smiles

CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1cc(OC)cc(OC)c1

Molecular Formula

C28H41N7O3

Molecular Weight

523.67

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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