PD173074
Product Specifications
CAS Number
219580-11-7
Target
FGFR|||EGFR|||Apoptosis|||VEGFR|||IGF-1R|||Src
Related Pathways
Angiogenesis|||Apoptosis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling
Purity
0.9821
Bioactivity
PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.
Smiles
CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1cc(OC)cc(OC)c1
Molecular Formula
C28H41N7O3
Molecular Weight
523.67
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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