Decernotinib
Product Specifications
CAS Number
944842-54-0
Target
Tyrosine Kinases, JAK
Related Pathways
Stem Cells, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic
Purity
>99.99%
Bioactivity
Decernotinib (VRT-831509) (VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.
Smiles
CC[C@@](C)(Nc1ccnc(n1)-c1c[nH]c2ncccc12)C(=O)NCC(F)(F)F
Molecular Formula
C18H19F3N6O
Molecular Weight
392.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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