Decernotinib

Product Specifications

CAS Number

944842-54-0

Target

Tyrosine Kinases|||JAK

Related Pathways

Stem Cells|||Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic

Purity

>99.99%

Bioactivity

Decernotinib (VRT-831509) (VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.

Smiles

CC[C@@](C)(Nc1ccnc(n1)-c1c[nH]c2ncccc12)C(=O)NCC(F)(F)F

Molecular Formula

C18H19F3N6O

Molecular Weight

392.38

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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