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(-) -Agelastatin A

Product Specifications

CAS Number

152406-28-5

Target

GSK-3, Apoptosis, Wnt/beta-catenin

Related Pathways

PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Apoptosis, Stem Cells

Purity

>99.99%

Bioactivity

(-) -Agelastatin A is a member of the pyrrole-aminoimidazole marine alkaloid (PAI) family, capable of inhibiting β-catenin, GSK-3β, and osteopontin (OPN), exhibiting antiproliferative activity against various cancers such as leukaemia and breast cancer, and possessing a certain ability to penetrate the central nervous system (CNS) .

Smiles

BrC=1N2[C@]3([C@]([C@]4([C@@](O)(C3)N(C)C(=O)N4)[H])(NC(=O)C2=CC1)[H])[H]

Molecular Formula

C12H13BrN4O3

Molecular Weight

341.16

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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