(-) -Agelastatin A
Product Specifications
CAS Number
152406-28-5
Target
GSK-3|||Apoptosis|||Wnt/beta-catenin
Related Pathways
PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling|||Apoptosis|||Stem Cells
Purity
>99.99%
Bioactivity
(-) -Agelastatin A is a member of the pyrrole-aminoimidazole marine alkaloid (PAI) family, capable of inhibiting ?-catenin, GSK-3?, and osteopontin (OPN), exhibiting antiproliferative activity against various cancers such as leukaemia and breast cancer, and possessing a certain ability to penetrate the central nervous system (CNS) .
Smiles
BrC=1N2[C@]3([C@]([C@]4([C@@](O)(C3)N(C)C(=O)N4)[H])(NC(=O)C2=CC1)[H])[H]
Molecular Formula
C12H13BrN4O3
Molecular Weight
341.16
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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