VU0285655-1
Product Specifications
CAS Number
1158347-73-9
Target
Phospholipase|||Interleukin|||TNF
Related Pathways
Metabolism|||Immunology/Inflammation|||Apoptosis
Purity
0.9973
Bioactivity
VU0285655-1 (BML-280) is a potent and selective phospholipase D2 (PLD2) inhibitor that inhibits the proliferation of PLD2-deficient cells.VU0285655-1 has an inhibitory effect on high glucose-induced caspase-3 cleavage and reduction of cell viability.VU0285655-1 is used in the study of diabetic retinopathy.
Smiles
O=C1C2(N(CN1)C3=CC=CC=C3)CCN(CCNC(=O)C4=CC5=C(N=C4)C=CC=C5)CC2
Molecular Formula
C25H27N5O2
Molecular Weight
429.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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