Poziotinib
Product Specifications
CAS Number
1092364-38-9
Target
Apoptosis, EGFR, HER
Related Pathways
JAK/STAT signaling, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors
Purity
0.9978
Bioactivity
Poziotinib (NOV120101) (NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM) .
Smiles
COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC1CCN(CC1)C(=O)C=C
Molecular Formula
C23H21Cl2FN4O3
Molecular Weight
491.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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