Poziotinib

Product Specifications

CAS Number

1092364-38-9

Target

Apoptosis|||EGFR|||HER

Related Pathways

JAK/STAT signaling|||Angiogenesis|||Apoptosis|||Tyrosine Kinase/Adaptors

Purity

0.9978

Bioactivity

Poziotinib (NOV120101) (NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM) .

Smiles

COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC1CCN(CC1)C(=O)C=C

Molecular Formula

C23H21Cl2FN4O3

Molecular Weight

491.34

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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