Surfen dihydrochloride
Product Specifications
CAS Number
5424-37-3
Target
Antibiotic, Antiviral, FGFR, VEGFR, HSV, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Microbiology/Virology, Immunology/Inflammation
Purity
0.9708
Bioactivity
Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulfate with antibacterial and antiviral activity, and inhibits anthrax lethal factor, coagulation factor X, and lethal factor.Surfen inhibits the anticoagulant activity of both normal and low-molecular-weight heparin and inhibits heparin sulfation and heparin cleavage enzyme degradation.Surfen inhibits the blockade of FGF2 binding and signaling mediated by heparin acetylsulfate. Surfen inhibits the blockade of acetylheparin sulfate-mediated FGF2 binding and signaling.Surfen inhibits SEVI and semen-mediated enhancement of HIV type 1 infection.
Smiles
Cl.Cl.Cc1cc(N)c2cc(NC(=O)Nc3ccc4nc(C)cc(N)c4c3)ccc2n1
Molecular Formula
C21H22Cl2N6O
Molecular Weight
445.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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