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Surfen dihydrochloride

Product Specifications

CAS Number

5424-37-3

Target

Antibiotic, Antiviral, FGFR, VEGFR, HSV, Microtubule Associated

Related Pathways

Cytoskeletal Signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Microbiology/Virology, Immunology/Inflammation

Purity

0.9708

Bioactivity

Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulfate with antibacterial and antiviral activity, and inhibits anthrax lethal factor, coagulation factor X, and lethal factor.Surfen inhibits the anticoagulant activity of both normal and low-molecular-weight heparin and inhibits heparin sulfation and heparin cleavage enzyme degradation.Surfen inhibits the blockade of FGF2 binding and signaling mediated by heparin acetylsulfate. Surfen inhibits the blockade of acetylheparin sulfate-mediated FGF2 binding and signaling.Surfen inhibits SEVI and semen-mediated enhancement of HIV type 1 infection.

Smiles

Cl.Cl.Cc1cc(N)c2cc(NC(=O)Nc3ccc4nc(C)cc(N)c4c3)ccc2n1

Molecular Formula

C21H22Cl2N6O

Molecular Weight

445.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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