AG490
Product Specifications
CAS Number
133550-30-8
Target
JAK, STAT, Autophagy, EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Autophagy, Angiogenesis, Stem Cells, JAK/STAT signaling, Chromatin/Epigenetic
Purity
0.9985
Bioactivity
AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50: 0.1 μM) . It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src.
Smiles
C(=C(/C(NCC1=CC=CC=C1)=O)\C#N)\C2=CC(O)=C(O)C=C2
Molecular Formula
C17H14N2O3
Molecular Weight
294.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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