Potassium guaiacolsulfonate (hemihydrate)

Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other agents[1][2].

Product Specifications

CAS Number

[78247-49-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H332

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/potassium-guaiacolsulfonate-hemihydrate.html

Purity

99.83

Solubility

H2O : 62.5 mg/mL (ultrasonic)

Smiles

COC1=CC(S(=O)(O[K])=O)=CC=C1O.COC2=C(C=CC=C2O)S(=O)(O[K])=O.[H]O[H]

Molecular Formula

C7H8O5S.1/2H2O.K

Molecular Weight

251.31

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Ozlem Aksu Dönmez, et al. Simultaneous Determination of Potassium Guaiacolsulfonate, Guaifenesin, Diphenhydramine HCl and Carbetapentane Citrate in Syrups by Using HPLC-DAD Coupled With Partial Least Squares Multivariate Calibration. Talanta. 2011 Feb 15;83 (5) :1601-5.|[2]Thi Huong Hoa Le, et al. Development and Validation of an HPLC Method for Simultaneous Assay of Potassium Guaiacolsulfonate and Sodium Benzoate in Pediatric Oral Powder. J Anal Methods Chem. 2019 Mar 7;2019:6143061.